Glavni žreb
6. jun 2021.
| Magda Linette - Ons Jabeur | 6:3, 0:6, 1:6 |
| Barbora Krejcikova - Elina Svitolina | 6:3, 6:2 |
| Sofia Kenin - Jessica Pegula | 4:6, 6:1, 6:4 |
| Maria Sakkari - Elise Mertens | 7:5, 6 (2):7 (7), 6:2 |
| Marta Kostyuk - Varvara Gracheva | 6:1, 6:2 |
| Anett Kontaveit - Iga Swiatek | 6 (4):7 (7), 0:6 |
| Serena Williams - Elena Rybakina | 3:6, 5:7 |
| Alexander Zverev - Kei Nishikori | 6:4, 6:1, 6:1 |
| Alejandro Davidovich Fokina - Federico Delbonis | 6:4, 6:4, 4:6, 6:4 |
| Victoria Azarenka - Anastasia Pavlyuchenkova | 7:5, 3:6, 2:6 |
| Stefanos Tsitsipas - Pablo Carreno Busta | 6:3, 6:2, 7:5 |
| Tamara Zidansek - Sorana Cirstea | 7 (7):6 (4), 6:1 |
| Cristian Garin - Daniil Medvedev | 2:6, 1:6, 5:7 |
| Marketa Vondrousova - Paula Badosa | 4:6, 6:3, 2:6 |
