Glavni žreb
9. jun 2021.
| Novak Đokovic - Matteo Berrettini | 6:3, 4:6, 6:4, 6:0 |
| Coco Gauff - Barbora Krejcikova | 6:7, 3:6 |
| Rafael Nadal - Diego Schwartzman | 6:3, 4:6, 6:4, 6:0 |
| Maria Sakkari - Iga Swiatek | 6:4, 6:4 |
| Alexander Zverev - Alejandro Davidovich Fokina | 6:4, 6:1, 6:1 |
| Elena Rybakina - Anastasia Pavlyuchenkova | 7 (7):6 (2), 2:6, 7:9 |
| Stefanos Tsitsipas - Daniil Medvedev | 6:3, 7 (7):6 (3), 7:5 |
